Polynucleotide Skin Regeneration Treatment
Next generation skin regeneration
What is the Polynucleotide Skin Regeneration Treatment?
Polynucleotides are an advanced injectable skin treatment designed to regenerate, repair and rejuvenate the skin from within. This innovative treatment works at a cellular level to improve skin quality, restore elasticity, and promote long-term skin health.
Unlike dermal fillers, polynucleotides do not add volume or alter facial structure. Instead, they stimulate the skin’s natural repair processes, delivering gradual, natural-looking results.
Treatment Areas
Face, under-eyes, neck, décolletage, hands.
What to Expect
Treatment time – 30 to 45 minutes
The skin is thoroughly cleansed, and a topical numbing cream may be applied to maximise comfort.
Using fine injections, polynucleotides are delivered into the targeted areas of the skin.
You may experience mild redness, slight swelling or small injection marks and tenderness in treated areas.
These effects are temporary and typically resolve within a few days. Results develop gradually as the skin regenerates over time, rather than instantly.
How It Works
Polynucleotides are highly purified DNA fragments derived from natural sources, which act as powerful bio-stimulators within the skin.
When injected into the dermis:
They stimulate fibroblasts, the cells responsible for producing collagen and elastin
They promote tissue repair and regeneration at a cellular level
They improve hydration by attracting and retaining water within the skin
They provide antioxidant and anti-inflammatory effects
This process helps rebuild the skin’s structure, improving elasticity, firmness, and overall skin function over time.
Polynucleotides work by supporting the skin’s extracellular matrix (the framework that keeps skin firm and youthful), allowing the skin to regenerate naturally rather than simply filling lines.
Benefits
Polynucleotide treatments focus on improving overall skin health, rather than providing immediate volume.
Over the weeks following treatment, the skin becomes:
Firmer and more elastic
Smoother and more refined
More hydrated and radiant
Results continue to improve as collagen production increases and tissue regeneration progresses.
Key Benefits & Indications
Stimulates collagen and elastin production for firmer, more resilient skin
Deep skin regeneration and repair at a cellular level
Improves skin texture, tone, and overall quality
Enhances hydration by attracting and retaining moisture
Reduces fine lines and early signs of ageing
Can help improve acne scars and skin damage
Anti-inflammatory and antioxidant effects for healthier skin
Provides natural, gradual rejuvenation without altering facial shape
Our Process
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Consultation
Every Polynucleotide treatment begins with an in-depth consultation and medical review. We take the time to understand your concerns, assess your skin quality and discuss your desired outcome, ensuring this advanced regenerative treatment is perfectly suited to you.
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Allergy Test
An allergy test is not required for this treatment.
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Day of Treatment
Using a series of expertly placed micro-injections, Polynucleotides are delivered into targeted areas to stimulate cellular renewal, enhance elasticity and deeply revitalise the skin. A topical numbing cream can be applied to ensure the experience is comfortable.
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Post-treatment
You may notice mild redness or slight swelling, which typically settles within 24–48 hours. Comprehensive aftercare guidance will be provided to support optimal results. For best outcomes, a course of treatments is recommended, with maintenance sessions advised to preserve long-term skin vitality.
Please read through our Pre Procedural Advice and Post Procedural Advice before booking, so you feel fully informed and know exactly what to expect.
Frequently Asked Questions
Everything you need to know about our Polynucleotide Skin Regeneration treatment.
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Our polynucleotide treatment is suitable for individuals who want to:
improve overall skin quality and firmness
treat early to moderate signs of ageing
improve skin damage, scarring, or pigmentation
achieve natural skin rejuvenation without volume enhancement
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Our polynucleotide treatment may not be suitable for:
pregnant or breastfeeding individuals
individuals with active skin infections or inflammation
people with fish allergies (due to the DNA source)
those with certain medical conditions (consultation required)
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Polynucleotide treatments are typically delivered as part of a structured course, tailored to the individual and treatment area.
a course of 3 treatments is recommended
treatments are spaced approximately 2 to 4 weeks apart to allow for tissue regeneration between sessions
frequency may be adjusted depending on skin condition, treatment area, and clinical goals
Following the initial course:
maintenance treatments are recommended every 6 to 9 months to sustain results
Polynucleotides may also be incorporated into combination treatment plans alongside other regenerative or aesthetic procedures where appropriate.
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No. Polynucleotides do not add volume or change facial structure. They work by improving skin quality and stimulating natural regeneration.
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Some improvement in hydration and skin texture may be noticed within a few weeks, with optimal results developing gradually as collagen and elastin support increases.
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Results can last several months depending on individual skin condition and lifestyle, with maintenance treatments recommended to help maintain results.
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There is minimal downtime. Mild redness, swelling, or tenderness may occur but typically settles within a few days.
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Discomfort is minimal. A numbing cream can be applied to ensure a comfortable experience.
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Yes. Polynucleotide treatments are often used alongside other aesthetic procedures to enhance overall results as part of a personalised treatment plan.
